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MYP_059625
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Basic Information
Periplanetasin-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
15 amino acids
C84H133N21O18S
Standard
Sequence
YPCKLNLKLGKVPFH
Physicochemical Analysis
1757.15 Da
9.63
2.83
2.56
0.1889
-0.16
0.38
0.07
9.91
97.33
0.1333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
623.20
-2.03
21.0
23.0
55.0
124.0
5.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0107523 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Refer PubMed ID: 28733329 [Candida albicans ATCC 90028 (
10 μM
MIC
PMID28173695;28733329;30554389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28173695/
RECORD: Rec_0112970 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Refer PubMed ID: 30554389 [Enterococcus faecium ATCC 19434 (
5 μM
MIC
PMID28173695;28733329;30554389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28173695/
RECORD: Rec_0116765 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
8 μg/mL
MIC
RECORD: Rec_0177707 VERIFIED: NO
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Antifungal Fungicide Anti-Candida Anti-Gram-negative Anti-Gram-positive Signal peptide Non-hemolytic Non-ribosomal
Aspergillus flavus, Aspergillus fumigatus, Candida albicans, Candida parapsilosis, Escherichia coli, Enterococcus faecalis, Enterococcus faecium, Malassezia furfur, Pseudomonas aeruginosa, Salmonella enteritidis, Staphylococcus epidermidis, Streptococcus mutans, Salmonella Typhimurium, Trichosporon beigelii
Qualitative functional evidence
PMID30554389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30554389/; https://www.uniprot.org/uniprotkb/C0HLK8/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0205236 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Refer PubMed ID: 28733329 [Candida albicans ATCC 90028 (
5 μM
MIC
PMID28173695;28733329;30554389 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28173695/
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