Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length451 amino acids

Chemical FormulaC2184H3413N601O689S10

DescriptionStandard

        MTQILGTGEGKTSSAAKEPVVERKPAQVFFESMALAASMSGYYAGPTATTLGNSLSLGAGTAAGVGEGVAGARVLAAPNPLTVALLAIFYSPSLNEGETETLQNIRGDQLYQNLIHGQMMMGAFTRVNSTVIEGDYVPEYELREIARQNGTVRTRVRFRIEEDPESGELVSRSYEVGEKSGLDRVRVRFAKQLDKETWGFEDPSIKGTFVWSRSAGQGKFEWGSSQTTVHDGSAGGYTTPPTPIPEPRSIWGLPNPAPASLPPVPGTPIPEEQGPNIETLPIEDRDFNDFIIVDPMGGVPAIYVYFQKASVRDLEVDYYENFEGRSRQGLYEVDHIPSKEAVRIYLKGTYPNLKDDIIEQMTDRVAAVAIPIEVHRQCSETYGGKNNSKFRTQDGGLVTQKVLDASNLEAAVDANWDVNAECLRNEYGVSDEKIEEIRAKLHELNRKAGLY
    

Molecular Weight49433.73 Da

Isoelectric Point (pI)4.90

Net Charge (pH 7.0)-17.98

Net Charge (pH 7.4) -18.62

Charge Density (pH 7.0) -0.0399

GRAVY Index-0.43

Hydrophobic Moment 0.64

Boman Index-0.01

Instability Index40.89

Aliphatic Index 77.63

Aromaticity 0.0820

Extinction Coeff. Reduced 54320.00

Extinction Coeff. Oxidized 54445.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421091 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)