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MYP_059615
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Basic Information
DNP (Dendroaspis natriuretic peptide)
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
38 amino acids
C180H284N56O56S2
Standard
Sequence
EVKYDPCFGHKIDRINHVSNLGCPSLRDPRPNAPSTSA
Physicochemical Analysis
4192.65 Da
8.14
0.99
0.69
0.0261
-0.78
0.54
-0.16
43.67
61.58
0.0526
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1791.02
-22.04
62.0
61.0
130.0
294.0
9.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0041618 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Natriuretic peptide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-23
Bio-Activity Profile
Natriuretic
Human kidney membrane extract, in vitro; 9540 s
PMID21459096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21459096/
RECORD: Rec_0196871 VERIFIED: YES
Provenance & Taxonomy
Dendroaspis angusticeps [Animal]
Natriuretic peptide DNP
8618
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation
Mammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Natriuretic peptide DNP (Dendroaspis angusticeps): PMID 18096107 PMID18096107 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18096107/
RECORD: Rec_0210157 VERIFIED: YES
Provenance & Taxonomy
Dendroaspis angusticeps [Animal]
Natriuretic peptide DNP
8618
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation
gastric antral circular smooth muscle cells
Mammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Natriuretic peptide DNP (Dendroaspis angusticeps): PMID 18096107 PMID18096107 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18096107/
RECORD: Rec_0334144 VERIFIED: YES
Provenance & Taxonomy
Dendroaspis angusticeps [Animal]
Natriuretic peptide DNP
8618
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation
atrial natriuretic peptide receptor
Mammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Natriuretic peptide DNP (Dendroaspis angusticeps): PMID 18096107 PMID18096107 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18096107/
RECORD: Rec_0372339 VERIFIED: NO
Provenance & Taxonomy
Dendroaspis angusticeps [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-23
Bio-Activity Profile
Neuropeptide