Peptide Database

Peptide NameP59, GBV-C E2 (175-192)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC93H146N28O24S

DescriptionStandard

        RFPFHRCGAGPKLTKDLE
    

Molecular Weight2072.39 Da

Isoelectric Point (pI)9.31

Net Charge (pH 7.0)1.84

Net Charge (pH 7.4) 1.57

Charge Density (pH 7.0) 0.1025

GRAVY Index-0.79

Hydrophobic Moment 0.43

Boman Index-0.20

Instability Index21.41

Aliphatic Index 48.89

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 839.79

LogP -7.09

H-bond Donors 30.0

H-bond Acceptors 28.0

Rotatable Bonds 66.0

Heavy Atoms 146.0

Ring Count 5.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0256847 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1:inhibition of gp41-induced cell-cell fusion in CEM-174 cells

Activity529.6 μM

MethodIC50

RECORD: Rec_0302320 VERIFIED: YES