Peptide Database

Peptide NameSyn-BNP (2. Ala9)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC45H84N14O10

DescriptionStandard

        KLGVPLKRA
    

Molecular Weight981.24 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.3065

GRAVY Index-0.08

Hydrophobic Moment 0.58

Boman Index-0.12

Instability Index47.64

Aliphatic Index 130.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 401.27

LogP -2.30

H-bond Donors 14.0

H-bond Acceptors 13.0

Rotatable Bonds 33.0

Heavy Atoms 69.0

Ring Count 1.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143488 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Other ModsHMA

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans

Activity32 μg/mL

MethodMIC

RECORD: Rec_0177017 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermC14OH

C-TermNone

Other Modsk=D-Lys; v=D-Val

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetHT-29

Activity>128 μg/mL

MethodLC

RECORD: Rec_0198586 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Other ModsHMA

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCryp. neoformans

Activity8 μg/mL

MethodMIC

RECORD: Rec_0198869 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermC14OH

C-TermNone

Other Modsk=D-Lys; v=D-Val

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0208997 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermC14OH

C-TermNone

Other Modsk=D-Lys; v=D-Val

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic