Peptide Database

Peptide NameRelease factor glutamine methyltransferase [145-151]

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC33H56N10O12

DescriptionStandard

        LRPEAAE
    

Molecular Weight784.86 Da

Isoelectric Point (pI)4.86

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.1756

GRAVY Index-0.81

Hydrophobic Moment 0.21

Boman Index-0.23

Instability Index88.43

Aliphatic Index 84.29

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 365.63

LogP -3.11

H-bond Donors 12.0

H-bond Acceptors 11.0

Rotatable Bonds 24.0

Heavy Atoms 55.0

Ring Count 1.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023420 VERIFIED: YES

Provenance & Taxonomy

OrganismVibrio cholerae [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity5.36 ± 0.75 μM

MethodIC50