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MYP_059567
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Metabolic ▸ Lipid metabolism ▸ Cholesterol-lowering
Standard
5 amino acids
C26H48N6O8
Standard
Sequence
IIAEK
Physicochemical Analysis
572.69 Da
6.00
-0.24
-0.44
-0.0476
0.68
0.25
0.23
8.00
176.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
243.04
-0.56
8.0
8.0
20.0
40.0
0.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0071183 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
63.7
IC50
PaperO. Power, A. Fern¨¢ndez, R. Norris, F.A. Riera, R.J. FitzGerald. Selective enrichment of bioactive properties during ultrafiltration of a tryptic digest of beta-lactoglobulin, J. Funct. Foods, 9 (2014), 38-47.
RECORD: Rec_0074954 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
63.7 μM
IC50
PaperSelective enrichment of bioactive properties during ultrafiltration of a tryptic digest of β-lactoglobulin | Power, O. et al. | DOI: 10.1016/j.jff.2014.04.002 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
RECORD: Rec_0116639 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cholesterol-regulating Hypocholesterolemic
Caco-2 cells
PaperIdentification of Novel Hypocholesterolemic Peptides Derived from Bovine Milk β-lactoglobulin | Nagaoka, S. et al. | DOI: 10.1006/bbrc.2001.4298 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
RECORD: Rec_0189875 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hypocholesterolemic
PMID7794873 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7794873/
RECORD: Rec_0395212 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive Hypocholesterolemic
Caco-2 cells
PaperIdentification of Novel Hypocholesterolemic Peptides Derived from Bovine Milk β-Lactoglobulin | Nagaoka, S. et al. | DOI: 10.1006/bbrc.2001.4298 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry