Peptide Database

Peptide NameToxin Pi2

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC169H273N53O48S7

DescriptionStandard

        TISCTNPKQCYPHCKKETGYPNAKCMNRKCKCFGR
    

Molecular Weight4039.76 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)6.42

Net Charge (pH 7.4) 6.08

Charge Density (pH 7.0) 0.1835

GRAVY Index-1.09

Hydrophobic Moment 0.66

Boman Index-0.32

Instability Index39.34

Aliphatic Index 14.00

Aromaticity 0.0857

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1665.99

LogP -20.64

H-bond Donors 63.0

H-bond Acceptors 63.0

Rotatable Bonds 133.0

Heavy Atoms 277.0

Ring Count 7.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323321 VERIFIED: NO

Provenance & Taxonomy

OrganismPandinus imperator [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-25; 10-30; 14-32

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0408515 VERIFIED: YES