Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 12

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC441H699N135O140S8

DescriptionStandard

        MRTLALLASLLLLVLHAQAQSLEERADHVPAQDQPGAEVQDMTISFAGDEPSSPYAAELQGTPTCHCRPFTCYSGESPSGHCEGKGFQRRRCCRR
    

Molecular Weight10388.61 Da

Isoelectric Point (pI)6.03

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.71

Charge Density (pH 7.0) -0.0230

GRAVY Index-0.44

Hydrophobic Moment 0.47

Boman Index-0.07

Instability Index72.62

Aliphatic Index 64.84

Aromaticity 0.0526

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4388.51

LogP -52.93

H-bond Donors 157.0

H-bond Acceptors 150.0

Rotatable Bonds 336.0

Heavy Atoms 724.0

Ring Count 16.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218885 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence