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MYP_059518
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Basic Information
Safencin (48-70)[G2W;E4,13K]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C144H243N43O30
Standard
Sequence
AWKKTIRQYLKNKIKKKGRKAVIAW
Physicochemical Analysis
3056.74 Da
11.36
9.79
9.59
0.3915
-0.98
0.70
-0.33
10.18
86.00
0.1200
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1251.90
-6.96
46.0
40.0
110.0
217.0
5.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0163993 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
10 μM
MIC
PMID29463889 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
RECORD: Rec_0252168 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human keratinocytes HaCat
10 μM
Cytotoxicity
PMID29463889 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
RECORD: Rec_0264324 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Xanthomonas axonopodis pv. phaseoli ATCC 9563
1 μM
MIC
PMID29463889 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
RECORD: Rec_0315062 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas syringae
PMID29463889 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
RECORD: Rec_0323903 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli BL21
8 μM
MIC
PMID29463889 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29463889/
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