Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length514 amino acids

Chemical FormulaC2538H3941N665O742S25

DescriptionStandard

        MNQKPEKPRGHLFTCRTDAKNHFPSCSDSGGPSNMFLSVTAVLMLFSCAHGENPAIQVILTNKGLQYGKHAGTDWIQKMLEHVTLPDISGKVNVGFWCSIHYTLTNTSIEKCDLPEPSADFYPDATGLKTSMSGLSVALSGQWMTHFGIIHDKGSFDMAILGVDVTSVVELGKDADGHLSVSSANCVAQVGDVDVRFHGGASWIFKRFVKHFKKRISKEIENRICPNVEELIASVEYHLQAMNVSFEVDPAMAMNLSLSTSPTIDVSSLNLGLKGEFFSEKTRADPPFEAQPFTMPEQQAFMLSWGLSEFTLNSASYVYYSYGVFQRFIDDSMIPPGFPLHLNTSLMGPYVPQLPKMFPGLLMDLHVYARDTPMFSFQPGAVKLGIQGAVKAFAIQPNGTQTPLFQLNIDLTLSSKVWIADGKVKGSVSTDNFTLTLAGSEVGSFGTDALENIARKVVEMGLEILNKRLGRGLVLPRLKRAQLVNSVLKVQEGFIALFSDADVFLTDRGFNQQN
    

Molecular Weight56443.07 Da

Isoelectric Point (pI)6.06

Net Charge (pH 7.0)-6.29

Net Charge (pH 7.4) -7.43

Charge Density (pH 7.0) -0.0122

GRAVY Index-0.03

Hydrophobic Moment 0.91

Boman Index0.12

Instability Index29.46

Aliphatic Index 85.33

Aromaticity 0.0953

Extinction Coeff. Reduced 47900.00

Extinction Coeff. Oxidized 48275.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164970 VERIFIED: NO

Provenance & Taxonomy

OrganismScophthalmus maximus [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence