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MYP_059416
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Basic Information
SAAP fraction 3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
7 amino acids
C28H37N7O22
Standard
Sequence
DDDDDDD
Physicochemical Analysis
823.63 Da
4.05
-7.23
-7.44
-1.0327
-3.50
0.03
-0.90
8.57
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
499.02
-7.37
15.0
15.0
27.0
57.0
0.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004531 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
allo-residue reported
Bio-Activity Profile
Antimicrobial
A recent study tested additional bacteria and found this peptide was inactive
>512 μg/mL
MIC
PaperIsolation of an ovine pulmonary surfactant-associated anionic peptide bactericidal for Pasteurella haemolytica.
RECORD: Rec_0061956 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 10031 (MBC50=0.62 mM in Zn-saline)
PMID8552650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8552650/
RECORD: Rec_0073852 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 12795 (MBC50=0.64 mM in Zn-saline)
PMID8552650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8552650/
RECORD: Rec_0103875 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pasteurella haemolytica (MBC50=0.02 mM in Zn-saline, MBC50=8.52 mM in Test buffer; Peptide/surfactant mixture MBC50=0.01 mM in Zn-saline, MBC50=4.43 mM in Test buffer; Peptide/serum mixture MBC50=0.02 mM in Zn-saline, MBC50=4.95 mM in Test buffer; Peptide/surfactant/serum mixture MBC50=0.03 mM in Zn-saline, MBC50=2.79 mM in Test buffer)
PMID8552650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8552650/
RECORD: Rec_0119643 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213 (MBC50=1.21 mM in Zn-saline)
PMID8552650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8552650/
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