Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC352H575N101O86S9

DescriptionStandard

        MKLLLLTLATLLLLSQLIPGDAQRCWNLRGKCRHRCSRKESVYVYCTNGRMCCVKPKYQPKPKPWMF
    

Molecular Weight7886.54 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1570

GRAVY Index-0.23

Hydrophobic Moment 0.44

Boman Index-0.09

Instability Index24.54

Aliphatic Index 85.82

Aromaticity 0.0896

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3025.89

LogP -22.79

H-bond Donors 113.0

H-bond Acceptors 107.0

Rotatable Bonds 260.0

Heavy Atoms 548.0

Ring Count 14.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192123 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrotus ochrogaster [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence