Peptide Database

Peptide NameSLAY-screened peptide P3983

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC110H167N31O28S

DescriptionStandard

        PSNCVIRWTLHGLPNTYYRL
    

Molecular Weight2403.76 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)2.03

Net Charge (pH 7.4) 1.91

Charge Density (pH 7.0) 0.1017

GRAVY Index-0.29

Hydrophobic Moment 0.51

Boman Index0.03

Instability Index32.96

Aliphatic Index 92.50

Aromaticity 0.1500

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 949.04

LogP -7.44

H-bond Donors 36.0

H-bond Acceptors 32.0

Rotatable Bonds 71.0

Heavy Atoms 170.0

Ring Count 7.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0271705 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/