Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length309 amino acids

Chemical FormulaC1473H2295N383O416S16

DescriptionStandard

        MQAAPGSRSPSAPCLAVTAKIDTTVGIDYSLTAPPVATAQFLNADLKGECFSLAQHTAIPFTPPALAFPPDHSRMVYFGVSSYFFNTASFAYHTAGALVFEITDSMIPKDIEFRLNTSTFAAFLPQVSPSPMYPNMPMKLRLSTPSAPFLSIGPDGVSLQPVVDIQAYAIYPNGSLAPLFLVSLVSWGPGLPWCPVSAACTSVSKGGRSGLLLCTAPCSLLLLVPTQPCVFSFPERLGKGFPLPLPAQVQLSDLLVQFHEVSGGSGACPATRPREAGVRRGAPRRGMKQISCTAVAQAGLRSADFKTGA
    

Molecular Weight32538.34 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)4.77

Net Charge (pH 7.4) 4.18

Charge Density (pH 7.0) 0.0154

GRAVY Index0.25

Hydrophobic Moment 0.64

Boman Index0.20

Instability Index53.20

Aliphatic Index 84.37

Aromaticity 0.0906

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326045 VERIFIED: NO

Provenance & Taxonomy

OrganismAnser brachyrhynchus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria