Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length192 amino acids

Chemical FormulaC956H1524N262O256S8

DescriptionStandard

        PKALPTAREPMLLLAVTDFVANSAAFTYFTAGVLHRNISSGMLPQRFPLQLRTKNMGVFSPQLQERYQDLPMELHLWARQQPLISCHPDALHGTLFGSAEAFVVLPNTTRVPVFLLNIDANVTGKPTITTNRLGGTVRLTGLPAPCIPLPALCLAQGLSVPQVKRLETLLKFGLWLFGVPRANSECRPHSVP
    

Molecular Weight21040.45 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)7.37

Net Charge (pH 7.4) 6.98

Charge Density (pH 7.0) 0.0384

GRAVY Index0.14

Hydrophobic Moment 0.54

Boman Index0.13

Instability Index51.01

Aliphatic Index 100.57

Aromaticity 0.0729

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8119.81

LogP -97.96

H-bond Donors 279.0

H-bond Acceptors 276.0

Rotatable Bonds 663.0

Heavy Atoms 1482.0

Ring Count 41.0

Amide Bonds 208.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008870 VERIFIED: NO

Provenance & Taxonomy

OrganismFormicarius rufipectus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria