Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC384H605N99O109S9

DescriptionStandard

        MKIIYIFLTFLITVSCGPSVSEKKRREIEERKRECYLVNGVCKTECNTWEYVYNYCNVEPCCVIREYQKPVM
    

Molecular Weight8641.09 Da

Isoelectric Point (pI)8.16

Net Charge (pH 7.0)1.44

Net Charge (pH 7.4) 1.09

Charge Density (pH 7.0) 0.0201

GRAVY Index-0.22

Hydrophobic Moment 0.58

Boman Index-0.05

Instability Index61.28

Aliphatic Index 80.97

Aromaticity 0.1250

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3398.60

LogP -25.68

H-bond Donors 126.0

H-bond Acceptors 120.0

Rotatable Bonds 286.0

Heavy Atoms 601.0

Ring Count 13.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0306496 VERIFIED: NO

Provenance & Taxonomy

OrganismLoxodonta africana [Animal]

FamilyDefensin

Tax ID9785

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence