Peptide Database

Peptide NameApolipophorin-3 (Apolipophorin-III) (ApoLp-III)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC883H1450N264O289S2

DescriptionStandard

        MAAKYVFVVAACSALAQAGIVRRDASTPLQDLEKHAAEFQKTFSEQLNAFTNSKDTKEFNTALKEGSDSVLQQLNALASSLQKALNDANGKAKEALEQTRTNLERTAEELRRAHPDVERQAGALRDRLQTAVQATVQETQKLAKTVGANLEETNKKLAPQIKSAYDDFVKQAQEVQKKLHEAASKQ
    

Molecular Weight20452.68 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)1.79

Net Charge (pH 7.4) 1.34

Charge Density (pH 7.0) 0.0096

GRAVY Index-0.67

Hydrophobic Moment 0.78

Boman Index-0.16

Instability Index37.99

Aliphatic Index 77.85

Aromaticity 0.0430

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9133.63

LogP -119.63

H-bond Donors 310.0

H-bond Acceptors 296.0

Rotatable Bonds 714.0

Heavy Atoms 1438.0

Ring Count 14.0

Amide Bonds 212.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204368 VERIFIED: YES

Provenance & Taxonomy

OrganismGalleria mellonella [Animal]

FamilyInsect apolipophorin-3

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0211772 VERIFIED: YES

Provenance & Taxonomy

OrganismGalleria mellonella [Animal]

FamilyInsect apolipophorin-3

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetS. cerevisiae

RECORD: Rec_0229889 VERIFIED: YES

Provenance & Taxonomy

OrganismGalleria mellonella [Animal]

FamilyInsect apolipophorin-3

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0259600 VERIFIED: YES

Provenance & Taxonomy

OrganismGalleria mellonella [Animal]

FamilyInsect apolipophorin-3

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetC. wickerhamii

RECORD: Rec_0276798 VERIFIED: YES

Provenance & Taxonomy

OrganismGalleria mellonella [Animal]

FamilyInsect apolipophorin-3

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetS. lutea (Gram-negative)

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