Peptide Database

Peptide NameAflibercept

Function Ontology

Anticancer

Standard StatusStandard

Sequence Length431 amino acids

Chemical FormulaC2159H3404N582O652S16

DescriptionStandard

        SDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVRVHEKDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG
    

Molecular Weight48458.67 Da

Isoelectric Point (pI)8.20

Net Charge (pH 7.0)3.63

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0084

GRAVY Index-0.46

Hydrophobic Moment 0.63

Boman Index-0.03

Instability Index39.22

Aliphatic Index 79.26

Aromaticity 0.0789

Extinction Coeff. Reduced 55350.00

Extinction Coeff. Oxidized 55975.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125231 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMonoclonal antibody

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGlycosylation

Bio-Activity Profile

Function

Anticancer

Half-LifeIntravitreal half life - 7.13 days