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MYP_059262
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Basic Information
Dermaseptin-TO
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C133H225N37O38S
Standard
Sequence
ALWKDLLKNVGIAAGKAALNKVTDMVNQ
Physicochemical Analysis
2982.50 Da
9.53
1.79
1.60
0.0641
0.15
0.59
0.12
5.67
118.57
0.0357
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1236.08
-10.74
41.0
41.0
103.0
209.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021636 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tomopterna [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
4 μM
MIC
PMID33582221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33582221/
RECORD: Rec_0050342 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tomopterna [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
8 μM
MIC
PMID33582221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33582221/
RECORD: Rec_0060797 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tomopterna [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis
128 μM
MIC
PMID33582221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33582221/
RECORD: Rec_0077525 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tomopterna [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
MRSA
64 μM
MIC
PMID33582221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33582221/
RECORD: Rec_0136537 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID33582221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33582221/
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