Peptide Database

Peptide NameGalactose N-acetylgalactosamine-binding lectin CEL-III (Gal GalNAc-binding lectin CEL-III) (CEL-III) (Hemolytic lectin CEL-III) (Lectin CEL-III)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length442 amino acids

Chemical FormulaC2079H3210N574O697S33

DescriptionStandard

        MVSLVPCGFAQVLCTNPLDIGELRNYKSKQCVDIVGNQGSGNIATHDCDGLSDQQIIMCGDGTIRNEARNYCFTPDGSGNANVMSSPCTLYPEIPSSQRWRLGRKKAFTDNGGIEQVATEIINLASGKCLDVEGSDGTGDIGVYDCQNLDDQYFYIRSRGPELFYGRLRNEKSDLCLDVEGSEGKGNVLMYSCEDNLDQWFRYYENGEIVNAKQGMCLDVEGSDGSGNVGIYRCDDLRDQMWSRPNAYCNGDYCSFLNKESNKCLDVSGDQGTGDVGTWQCDGLPDQRFKWVFDDWEVPTATWNMVGCDQNGKVSQQISNTISFSSTVTAGVAVEVSSTIEKGVIFAKASVSVKVTASLSKAWTNSQSGTTAITYTCDNYDSDEEFTRGCMWQLAIETTEVKSGDLLVWNPQIIKCTRSNTAPGCAPFTKCANEDCTFCTDI
    

Molecular Weight48455.30 Da

Isoelectric Point (pI)4.40

Net Charge (pH 7.0)-25.59

Net Charge (pH 7.4) -26.33

Charge Density (pH 7.0) -0.0579

GRAVY Index-0.41

Hydrophobic Moment 0.65

Boman Index-0.01

Instability Index39.48

Aliphatic Index 66.79

Aromaticity 0.0882

Extinction Coeff. Reduced 77350.00

Extinction Coeff. Oxidized 78850.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031064 VERIFIED: YES

Provenance & Taxonomy

OrganismCucumaria echinata [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Antiplasmodial Cytolytic Lectin Cytotoxic Hemolytic

TargetP. falciparum

RECORD: Rec_0126221 VERIFIED: YES

Provenance & Taxonomy

OrganismCucumaria echinata [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Antiplasmodial Cytolytic Lectin Cytotoxic Hemolytic

TargetP. berghei

RECORD: Rec_0188807 VERIFIED: YES

Provenance & Taxonomy

OrganismCucumaria echinata [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Antiplasmodial Cytolytic Lectin Cytotoxic Hemolytic

TargetA. stephensi

RECORD: Rec_0229739 VERIFIED: YES

Provenance & Taxonomy

OrganismCucumaria echinata [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Antiplasmodial Cytolytic Lectin Cytotoxic Hemolytic

TargetAfrican green