Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC536H868N144O152S4

DescriptionStandard

        MFGTIGSPVKYNQNELSNSNIQTLEKSSLEVNLAKIINKYSKKTTWNQAQKKASKIVNMVMTGSDVASAISIVLGAFSFGTVTAIAWAARMSLKWYIKRKGKKAAVTW
    

Molecular Weight11889.76 Da

Isoelectric Point (pI)10.26

Net Charge (pH 7.0)11.49

Net Charge (pH 7.4) 11.25

Charge Density (pH 7.0) 0.1064

GRAVY Index-0.11

Hydrophobic Moment 0.69

Boman Index0.06

Instability Index14.92

Aliphatic Index 86.76

Aromaticity 0.0926

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4851.04

LogP -49.35

H-bond Donors 171.0

H-bond Acceptors 168.0

Rotatable Bonds 407.0

Heavy Atoms 836.0

Ring Count 15.0

Amide Bonds 119.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0104011 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus pumilus [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal