‹ ›
MYP_059195
← PREVIOUS NEXT → BACK
Basic Information
Pleurocidin [H11A][H15A][H23A]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C120H186N30O29
Standard
Sequence
GWGSFFKKAAAVGKAVGKAALTAYL
Physicochemical Analysis
2512.94 Da
10.18
3.76
3.54
0.1502
0.53
0.48
0.31
-9.21
82.40
0.1600
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
942.28
-6.85
34.0
33.0
81.0
179.0
5.0
24.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0037206 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis IFO 3143
8 μg/mL
MIC
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0085363 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
15 % hemolysis at 100 μM
Hemolysis
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0114168 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
100 μM
Hemolysis
PaperYoshida K, Mukai Y, Niidome T, et al. Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity. J Pept Res. 2001 Feb;57(2):119-126. doi:10.1034/j.1399-3011.2001.00802.x. PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0193047 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus IFO 12732
16 μg/mL
MIC
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0349270 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 64.0%, E 0.0%, T 16.0%, C 20.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2