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MYP_059194
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Basic Information
Umami peptide EL
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Sensory / Food function ▸ Taste-active peptide ▸ Umami peptide
Standard
2 amino acids
C11H20N2O5
Standard
Sequence
EL
Physicochemical Analysis
260.29 Da
4.05
-1.16
-1.33
-0.5816
0.15
0.70
0.16
5.00
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
129.72
-0.21
4.0
4.0
8.0
18.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0321566 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV
HIV
PaperNovel Methods of Synthesis for Therapeutic Antiviral Peptides Evidence URLhttps://patents.google.com/patent/US20100261876A1/en PatentUS 20100261876 A1
RECORD: Rec_0323271 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Glutamyl oligopeptide
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Bitter
PaperTaste of L-glutamyl oligopeptides in relation to their chromatographic properties. Agric. Biol. Chem., 37, 151-156, 1973
RECORD: Rec_0364882 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Colletotrichum acutatum
0.03 μM
MIC
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0371030 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
The N-terminal C14 fatty acid is a 3-hydroxy-11-methyltridecanoic acid (HTDA)
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
S. typhi
0.06 μM
MIC
PaperGageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis.
RECORD: Rec_0377986 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human prostate adenocarcinoma PC-3
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
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