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MYP_059194
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Basic Information
Umami peptide EL
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Sensory / Food function ▸ Taste-active peptide ▸ Umami peptide
Standard
2 amino acids
C11H20N2O5
Standard
Sequence
EL
Physicochemical Analysis
260.29 Da
4.05
-1.16
-1.33
-0.5816
0.15
0.70
0.16
5.00
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
129.72
-0.21
4.0
4.0
8.0
18.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0260899 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human gastric cancer NUGC-3
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0268849 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Superoxide scavenging
63.1 μM
IC50
PaperIsolation and characterization of free radical scavenging activities peptides derived from casein | Suetsuna, K. et al. | DOI: 10.1016/s0955-2863(99)00083-2 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0294330 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Salmonella typhi
0.06 μM
MIC
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0296859 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
The N-terminal C14 fatty acid is a 3-hydroxy-11-methyltridecanoic acid (HTDA)
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
C. acutatum
0.03 μM
MIC
PaperGageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis.
RECORD: Rec_0299217 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human breast adenocarcinoma MDA-MB-231
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
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