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MYP_059194
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Basic Information
Umami peptide EL
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Sensory / Food function ▸ Taste-active peptide ▸ Umami peptide
Standard
2 amino acids
C11H20N2O5
Standard
Sequence
EL
Physicochemical Analysis
260.29 Da
4.05
-1.16
-1.33
-0.5816
0.15
0.70
0.16
5.00
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
129.72
-0.21
4.0
4.0
8.0
18.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0160922 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human colon adenocarcinoma HCT-15
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0179463 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
The N-terminal C14 fatty acid is a 3-hydroxy-11-methyltridecanoic acid (HTDA)
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
ed Staphylococcus aureus
0.03 μM
MIC
PaperGageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis.
RECORD: Rec_0207665 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
The N-terminal C14 fatty acid is a 3-hydroxy-11-methyltridecanoic acid (HTDA)
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Pseudomonas aeruginosa
0.06 μM
MIC
PaperGageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis.
RECORD: Rec_0221735 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
0.03 μM
MIC
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0244098 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US20100261876A1/en PatentUS 2010/0261876 A1
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