Peptide Database

Peptide NameConopeptide X11.1 (I1_xm11a)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC354H579N105O107S11

DescriptionStandard

        MMKLSVSFLLLLMLLPFITGEENSDSDVLKSGAAVRQGRGRCRGFREDCSQHRDCCGDLCCNGNTCVITVIACPKW
    

Molecular Weight8370.74 Da

Isoelectric Point (pI)7.52

Net Charge (pH 7.0)0.52

Net Charge (pH 7.4) 0.12

Charge Density (pH 7.0) 0.0068

GRAVY Index0.09

Hydrophobic Moment 0.62

Boman Index0.01

Instability Index24.40

Aliphatic Index 84.61

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3418.09

LogP -37.61

H-bond Donors 128.0

H-bond Acceptors 120.0

Rotatable Bonds 281.0

Heavy Atoms 577.0

Ring Count 8.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393561 VERIFIED: YES

Provenance & Taxonomy

OrganismConasprella ximenes [other]

FamilyConotoxin I1

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-tuberculosis Anti-Gram-positive Non-hemolytic

TargetMycobacterium tuberculosis