Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length197 amino acids

Chemical FormulaC953H1552N248O280S7

DescriptionStandard

        MAVLSENNACSLLATTFNLNTALFKGLVPTIALSYLPACLVVLNLVATSPPAVSLNADRCILQITGCVDVFAVLPNSTTQYIFTGNLTASTRANLTITKQKLIISLLLKRLQFSLLRSTLGFSDQISLVENFLSYALRSAVIPVINDKLGKGFPLPNLADTTLTGPVIKMNQGHLVISTDVHYKHEKGGDEDLHSCS
    

Molecular Weight21188.47 Da

Isoelectric Point (pI)8.29

Net Charge (pH 7.0)1.81

Net Charge (pH 7.4) 1.28

Charge Density (pH 7.0) 0.0092

GRAVY Index0.40

Hydrophobic Moment 0.60

Boman Index0.20

Instability Index39.14

Aliphatic Index 118.78

Aromaticity 0.0609

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8401.49

LogP -111.11

H-bond Donors 292.0

H-bond Acceptors 293.0

Rotatable Bonds 695.0

Heavy Atoms 1488.0

Ring Count 25.0

Amide Bonds 215.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365671 VERIFIED: NO

Provenance & Taxonomy

OrganismPatagioenas fasciata monilis [Animal]

FamilyBPI/LBP

Tax ID372326

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria