Peptide Database

Peptide NameCycloviolacin O25

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC123H193N31O38S6

DescriptionStandard

        CGESCVFIPCLTSLAGCSCKNKVCYYN
    

Molecular Weight2906.42 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0259

GRAVY Index0.51

Hydrophobic Moment 0.29

Boman Index0.18

Instability Index48.80

Aliphatic Index 68.52

Aromaticity 0.1111

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1108.03

LogP -12.81

H-bond Donors 44.0

H-bond Acceptors 45.0

Rotatable Bonds 91.0

Heavy Atoms 198.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0169789 VERIFIED: YES

Provenance & Taxonomy

OrganismPalicourea rigida [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)