Peptide Database

Peptide NameSLAY-screened peptide P3657

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC105H159N35O31

DescriptionStandard

        HRSHNSTVYSYVRNRYIPTG
    

Molecular Weight2407.60 Da

Isoelectric Point (pI)10.27

Net Charge (pH 7.0)2.93

Net Charge (pH 7.4) 2.62

Charge Density (pH 7.0) 0.1466

GRAVY Index-1.19

Hydrophobic Moment 0.36

Boman Index-0.28

Instability Index36.26

Aliphatic Index 48.50

Aromaticity 0.1500

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1098.51

LogP -13.84

H-bond Donors 41.0

H-bond Acceptors 36.0

Rotatable Bonds 73.0

Heavy Atoms 171.0

Ring Count 6.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135346 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/