Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC363H582N98O99S9

DescriptionStandard

        MTQLLLLIVALLVLGHVPPGRSEFKQCWKGQGACGTYCTRHETYMHMCPDASLCCVAYGIRPLPLNLNLKTESV
    

Molecular Weight8191.69 Da

Isoelectric Point (pI)8.28

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.24

Charge Density (pH 7.0) 0.0231

GRAVY Index0.26

Hydrophobic Moment 0.48

Boman Index0.16

Instability Index55.12

Aliphatic Index 98.78

Aromaticity 0.0676

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3096.44

LogP -25.67

H-bond Donors 112.0

H-bond Acceptors 113.0

Rotatable Bonds 262.0

Heavy Atoms 569.0

Ring Count 14.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337640 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera tigris altaica [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence