Peptide Database

Peptide NameRWDISQPY

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC49H69N13O14

DescriptionStandard

        RWDISQPY
    

Molecular Weight1064.15 Da

Isoelectric Point (pI)5.84

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0300

GRAVY Index-1.45

Hydrophobic Moment 0.13

Boman Index-0.24

Instability Index128.50

Aliphatic Index 48.75

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 456.77

LogP -2.99

H-bond Donors 16.0

H-bond Acceptors 14.0

Rotatable Bonds 30.0

Heavy Atoms 76.0

Ring Count 4.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041176 VERIFIED: YES

Provenance & Taxonomy

OrganismSargassum maclurei [Protist]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory Antihypertensive

TargetACE; spontaneously hypertensive rat

Activity72.24 μM

MethodIC50