Peptide Database

Peptide NameProlixicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC365H564N130O122S

DescriptionStandard

        SPRPDDKKNQGSASVDVQNERGEGTKVDARVRQELWRSDDGRTRAQAYGHWDRTYGGRNHGERSYGGGMRIEHTWGN
    

Molecular Weight8757.25 Da

Isoelectric Point (pI)9.29

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.36

Charge Density (pH 7.0) 0.0226

GRAVY Index-1.66

Hydrophobic Moment 0.53

Boman Index-0.42

Instability Index23.13

Aliphatic Index 30.39

Aromaticity 0.0779

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 20970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4184.79

LogP -56.73

H-bond Donors 150.0

H-bond Acceptors 128.0

Rotatable Bonds 294.0

Heavy Atoms 618.0

Ring Count 14.0

Amide Bonds 84.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0362947 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0413866 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetE. aerogenes

Activity12.5 μM

MethodMIC

FIRST PREV 1 2 3

Showing 2 records on this page Ã‚Â· Page 3 of 3