Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC97H144N24O37S4

DescriptionStandard

        GIVEQCCDTPCSLYDPENYCN
    

Molecular Weight2366.58 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-4.27

Net Charge (pH 7.4) -4.54

Charge Density (pH 7.0) -0.2035

GRAVY Index-0.46

Hydrophobic Moment 0.37

Boman Index0.00

Instability Index25.00

Aliphatic Index 50.95

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 987.13

LogP -11.83

H-bond Donors 35.0

H-bond Acceptors 37.0

Rotatable Bonds 71.0

Heavy Atoms 162.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030527 VERIFIED: YES

Provenance & Taxonomy

OrganismPolypterus senegalus [Animal]

FamilyInsulin

Tax ID55291

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour