Peptide Database

Peptide NameNeurotoxin MeuNaTx-5 (Arthropods, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC314H473N87O91S8

DescriptionStandard

        ARDAYIAKPHNCVYECFDAFSSYCNGVCTKNGAKSGYCQILGTYGNGCWCIALPDNVPIRIPGKCH
    

Molecular Weight7179.16 Da

Isoelectric Point (pI)8.19

Net Charge (pH 7.0)1.89

Net Charge (pH 7.4) 1.46

Charge Density (pH 7.0) 0.0286

GRAVY Index-0.11

Hydrophobic Moment 0.47

Boman Index0.09

Instability Index24.83

Aliphatic Index 63.64

Aromaticity 0.1212

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2830.73

LogP -30.20

H-bond Donors 104.0

H-bond Acceptors 103.0

Rotatable Bonds 223.0

Heavy Atoms 500.0

Ring Count 15.0

Amide Bonds 71.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0011428 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0047342 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

FamilySodium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-65; 16-38; 24-48; 28-50

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense

RECORD: Rec_0308724 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetBacillus subtilis CGMCC 1.2428

RECORD: Rec_0401437 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMicrococcus luteus CGMCC 1.0290

RECORD: Rec_0407836 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus eupeus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetBacillus megaterium CGMCC 1.0459