Peptide Database

Peptide NameUnnamed

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC17H29N5O6

DescriptionStandard

        GPIN
    

Molecular Weight399.44 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0600

GRAVY Index-0.25

Hydrophobic Moment 0.32

Boman Index0.30

Instability Index7.50

Aliphatic Index 97.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 184.92

LogP -2.09

H-bond Donors 5.0

H-bond Acceptors 6.0

Rotatable Bonds 10.0

Heavy Atoms 28.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0175177 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antidiabetic DPP-IV inhibitory

TargetDipeptidyl peptidase IV

Activity48.96 μM

MethodIC50

PaperHarnedy-Rothwell P. A., McLaughlin C. M., O¡¯Keeffe M. B., le Gouic A. v., Allsopp P. J., McSorley E. M., Sharkey S., Whooley J., McGovern B., et al.. Identification and characterisation of peptides from a boarfish (capros aper) protein hydrolysate displaying in vitro dipeptidyl peptidase-IV (DPP-IV) inhibitory and insulinotropic activity. Food Research International, 131, 108989, 2020.