Peptide Database

Peptide NameProgonadoliberin IIB

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC322H505N91O92S2

DescriptionStandard

        QHWSHGWYPGGKREIDVYDPSEVSEEIKLCNAGKCSFLIPQGRNILKTILLDALTRDFQKRK
    

Molecular Weight7187.14 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)1.92

Net Charge (pH 7.4) 1.57

Charge Density (pH 7.0) 0.0310

GRAVY Index-0.66

Hydrophobic Moment 0.71

Boman Index-0.11

Instability Index57.45

Aliphatic Index 81.77

Aromaticity 0.0968

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2980.40

LogP -26.41

H-bond Donors 105.0

H-bond Acceptors 98.0

Rotatable Bonds 241.0

Heavy Atoms 507.0

Ring Count 13.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0328635 VERIFIED: YES

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyProgonadoliberin IIB

Tax ID7957

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour