Peptide Database

Peptide NameAlpha-1-proteinase inhibitor

Function Ontology

Antiviral

Hemostasis ▸ Fibrinolytic activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length394 amino acids

Chemical FormulaC2001H3130N514O601S10

DescriptionStandard

        EDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQK
    

Molecular Weight44323.99 Da

Isoelectric Point (pI)5.37

Net Charge (pH 7.0)-13.97

Net Charge (pH 7.4) -14.94

Charge Density (pH 7.0) -0.0354

GRAVY Index-0.30

Hydrophobic Moment 0.78

Boman Index0.04

Instability Index29.39

Aliphatic Index 87.11

Aromaticity 0.0888

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 19940.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008290 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyEnzyme

Tax ID9606

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Enzyme replacement Thrombolytic Fibrinolytic

RECORD: Rec_0203356 VERIFIED: NO