Peptide Database

Peptide NameFMRFamide-related peptide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC110H173N29O44

DescriptionStandard

        SDPDLDDVIRASLLAYSLDDSPNN
    

Molecular Weight2605.72 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.53

Net Charge (pH 7.4) -5.75

Charge Density (pH 7.0) -0.2306

GRAVY Index-0.53

Hydrophobic Moment 0.49

Boman Index-0.07

Instability Index32.77

Aliphatic Index 101.67

Aromaticity 0.0417

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1188.07

LogP -14.73

H-bond Donors 39.0

H-bond Acceptors 39.0

Rotatable Bonds 82.0

Heavy Atoms 183.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0100184 VERIFIED: YES

Provenance & Taxonomy

OrganismHaliotis asinina [Animal]

FamilyFMRFamide related peptide

Tax ID109174

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0124013 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0412399 VERIFIED: YES

Provenance & Taxonomy

OrganismHaliotis asinina [Animal]

FamilyFMRFamide-related peptide

Tax ID109174

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour