Peptide Database

Peptide NameEsculentin-1SEb

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Adverse immune reactivity ▸ Histamine-release modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Immunology ▸ Innate immune modulation ▸ Mast cell modulation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC224H382N60O60S2

DescriptionStandard

        GLFSKFNKKKIKSGLFKIIKTAGKEAGLEALRTGIDVIGCKIKGEC
    

Molecular Weight4939.93 Da

Isoelectric Point (pI)9.87

Net Charge (pH 7.0)6.74

Net Charge (pH 7.4) 6.49

Charge Density (pH 7.0) 0.1465

GRAVY Index-0.03

Hydrophobic Moment 0.67

Boman Index0.02

Instability Index5.31

Aliphatic Index 97.61

Aromaticity 0.0652

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1968.13

LogP -16.36

H-bond Donors 71.0

H-bond Acceptors 69.0

Rotatable Bonds 181.0

Heavy Atoms 346.0

Ring Count 3.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400156 VERIFIED: YES

Provenance & Taxonomy

OrganismDusky gopher [Animal]

FamilyEsculentin

Tax ID33208

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide40-46

Bio-Activity Profile

Function

Antimicrobial

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