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MYP_058840
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Basic Information
Esculentin-1SEb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Adverse immune reactivity ▸ Histamine-release modulation
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
46 amino acids
C224H382N60O60S2
Standard
Sequence
GLFSKFNKKKIKSGLFKIIKTAGKEAGLEALRTGIDVIGCKIKGEC
Physicochemical Analysis
4939.93 Da
9.87
6.74
6.49
0.1465
-0.03
0.67
0.02
5.31
97.61
0.0652
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1968.13
-16.36
71.0
69.0
181.0
346.0
3.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037950 VERIFIED: YES
Provenance & Taxonomy
Lithobates sevosus [Animal]
Frog skin active peptide (FSAP); Esculentin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Non-hemolytic
Micrococcus luteus (Gram-negative)
PMID16386333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16386333/
RECORD: Rec_0046512 VERIFIED: NO
Provenance & Taxonomy
Rana sevosa [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli and, Mycobacterium luteus
RECORD: Rec_0072421 VERIFIED: YES
Provenance & Taxonomy
Rana sevosa [Animal]
Esculentin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli K12
PaperPubMed PMID: 16386333 PMID16386333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16386333/
RECORD: Rec_0109811 VERIFIED: YES
Provenance & Taxonomy
Rana sevosa [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli dia 30 mm2)
PaperHistamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosai
RECORD: Rec_0130008 VERIFIED: YES
Provenance & Taxonomy
Lithobates sevosus [Animal]
Frog skin active peptide (FSAP); Esculentin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Non-hemolytic
Escherichia coli (Gram-negative)
PMID16386333 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16386333/
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