‹ ›
MYP_058830
← PREVIOUS NEXT → BACK
Basic Information
Apicidin A
Antimicrobial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Toxoplasma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
not Standard
4 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
WIXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0127347 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cyclic tetrapeptide
32630
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Pipecolinyl, 2-amino-8-oxodecanoyl
Bio-Activity Profile
Antimicrobial Antiprotozoal Antiparasitic Anti-Neospora
Neospora caninum
0.03 μg/mL
MIC; [3H] Uracil incorporation assay
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
RECORD: Rec_0133925 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cyclic tetrapeptide
32630
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Pipecolinyl, 2-amino-8-oxodecanoyl
Bio-Activity Profile
Antimicrobial Antiprotozoal Antiparasitic Anticoccidial
Eimeria tenella
0.031 μg/mL
MIC; [3H] Uracil incorporation assay
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
RECORD: Rec_0165941 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cyclic tetrapeptide
32630
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Pipecolinyl, 2-amino-8-oxodecanoyl
Bio-Activity Profile
Antimicrobial Antiprotozoal Antiparasitic Anti-Toxoplasma
Toxoplasma gondii
0.015 μg/mL
MIC; [3H] Uracil incorporation assay
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
RECORD: Rec_0181730 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cyclic tetrapeptide
32630
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Pipecolinyl, 2-amino-8-oxodecanoyl
Bio-Activity Profile
Antimicrobial Antiprotozoal Antiparasitic Antimalarial
Plasmodium falciparum
0.125 μg/mL
MIC
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
RECORD: Rec_0193463 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cyclic tetrapeptide
32630
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Pipecolinyl, 2-amino-8-oxodecanoyl
Bio-Activity Profile
Antimicrobial Antiprotozoal Antiparasitic Anti-Besnoitia
Besnoitia jellisoni
0.001 μg/mL
MIC; [3H] Uracil incorporation assay
PaperApicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase PMID8917558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8917558/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2