Peptide Database

Peptide NameBeta-defensin 103A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC345H570N104O83S7

DescriptionStandard

        MRIHYLLFTLLFLFLVPVPGHGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
    

Molecular Weight7727.32 Da

Isoelectric Point (pI)10.15

Net Charge (pH 7.0)11.61

Net Charge (pH 7.4) 11.19

Charge Density (pH 7.0) 0.1733

GRAVY Index-0.04

Hydrophobic Moment 0.63

Boman Index-0.06

Instability Index55.16

Aliphatic Index 94.48

Aromaticity 0.0896

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3031.94

LogP -24.44

H-bond Donors 116.0

H-bond Acceptors 104.0

Rotatable Bonds 260.0

Heavy Atoms 539.0

Ring Count 11.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307051 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9595

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence