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MYP_058802
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Basic Information
Brevinin-2HS2 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
33 amino acids
C143H255N39O45S2
Standard
Sequence
SLLGTVKDLLIGAGKSAAQSVLKGLSCKLSKDC
Physicochemical Analysis
3304.92 Da
9.24
2.44
2.19
0.0739
0.41
0.54
0.13
16.58
121.21
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1363.69
-15.76
50.0
50.0
118.0
229.0
0.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0153505 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0206834 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
R.rhodochrous X15
9.5 μM
MIC
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
RECORD: Rec_0209504 VERIFIED: YES
Provenance & Taxonomy
Huia schmackeri [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Slime mould 090223
37.5 μM
MIC
PMID18423796 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18423796/
RECORD: Rec_0209812 VERIFIED: YES
Provenance & Taxonomy
Huia schmackeri [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Rhodococcus rhodochrous X15
9.5 μM
MIC
PMID18423796 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18423796/
RECORD: Rec_0255820 VERIFIED: YES
Provenance & Taxonomy
Huia schmackeri [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human erythrocytes
300 μM
LC50
PMID18423796 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18423796/
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