Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1342H2104N338O385S6

DescriptionStandard

        MEKPILKNLNGMLCPIITNEVEALNVNLSTLEVLTKIDNYTLLDYSLVGPPEITEHYLNLNLRGVFYPLENLADPPFSPVPFVLPERSDSMIYIGISEYFFKSASFAHFVAGAFGVTLSTKEISKHFIQNSQGLGNVLSQVASTSVGLAILGQRLICSLSLKRFRLTVPESNRSDIKVLRFENILSSILHFGVLPLANTKLQQGFPLPNPHKLSFVNSDIEVLEGFLLISTDLKYETSSKQQPSFHGWEDLSLLNGQWMGKAAP
    

Molecular Weight29325.48 Da

Isoelectric Point (pI)5.87

Net Charge (pH 7.0)-3.96

Net Charge (pH 7.4) -4.57

Charge Density (pH 7.0) -0.0150

GRAVY Index0.10

Hydrophobic Moment 0.59

Boman Index0.16

Instability Index42.52

Aliphatic Index 107.05

Aromaticity 0.0947

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114075 VERIFIED: NO

Provenance & Taxonomy

OrganismSciurus vulgaris [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence