Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC367H601N97O104S8

DescriptionStandard

        MKLILLFLTVTLPLAQVIPVTKCWGKSGRCRTMCKESEVFYILCNAEAKCCVNPKYVPVNTGSSNSSGSLREPPAV
    

Molecular Weight8292.81 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.12

Charge Density (pH 7.0) 0.0585

GRAVY Index0.22

Hydrophobic Moment 0.61

Boman Index0.11

Instability Index41.94

Aliphatic Index 92.24

Aromaticity 0.0658

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3198.56

LogP -31.01

H-bond Donors 116.0

H-bond Acceptors 117.0

Rotatable Bonds 268.0

Heavy Atoms 576.0

Ring Count 12.0

Amide Bonds 80.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0013015 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinolophus ferrumequinum [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

PaperThe Genome 10K Project: a way forward; Bat Biology, Genomes, and the Bat1K Project: To Generate Chromosome-Level Genomes for All Living Bat Species; Six reference-quality genomes reveal evolution of bat adaptations PMID25689317;29166127;32699395 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/?term=25689317+OR+29166127+OR+32699395