Peptide Database

Peptide NameEK1

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor cross

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC196H317N43O64S

DescriptionStandard

        SLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKEL
    

Molecular Weight4331.93 Da

Isoelectric Point (pI)4.36

Net Charge (pH 7.0)-5.52

Net Charge (pH 7.4) -5.76

Charge Density (pH 7.0) -0.1534

GRAVY Index-0.43

Hydrophobic Moment 0.75

Boman Index-0.05

Instability Index22.73

Aliphatic Index 119.17

Aromaticity 0.0833

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1772.25

LogP -9.98

H-bond Donors 59.0

H-bond Acceptors 60.0

Rotatable Bonds 156.0

Heavy Atoms 304.0

Ring Count 3.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0427153 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman coronavirus OC43 [Virus]

FamilyHR2-derived fusion inhibitor

Tax ID31631

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetMiddle East respiratory syndrome-related coronavirus

Activity0.26 μM

MethodIC50

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