Peptide Database

Peptide Namevenom natriuretic peptide OsNP-d

Function Ontology

Antimicrobial

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC178H286N52O56S2

DescriptionStandard

        SDPKIGNGCFGFPIDRIGSVSGLGCNRLVQNPPKPISGES
    

Molecular Weight4114.62 Da

Isoelectric Point (pI)7.78

Net Charge (pH 7.0)0.44

Net Charge (pH 7.4) 0.20

Charge Density (pH 7.0) 0.0111

GRAVY Index-0.29

Hydrophobic Moment 0.72

Boman Index0.05

Instability Index9.82

Aliphatic Index 73.00

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1715.52

LogP -22.36

H-bond Donors 58.0

H-bond Acceptors 59.0

Rotatable Bonds 131.0

Heavy Atoms 288.0

Ring Count 7.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0068702 VERIFIED: YES

Provenance & Taxonomy

OrganismOxyuranus scutellatus scutellatus [Animal]

Familyvenom natriuretic peptide OsNP

Tax ID8667

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0073456 VERIFIED: YES

Provenance & Taxonomy

OrganismOxyuranus microlepidotus [Animal]

Familynatriuretic peptide OmNP

Tax ID111177

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0232483 VERIFIED: NO

Provenance & Taxonomy

OrganismOxyuranus scutellatus [Animal]; Oxyuranus microlepidotus [Animal]; Pseudechis australis [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0355352 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudechis australis [Animal]

Familynatriuretic peptide PaNP

Tax ID8670

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour