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MYP_058680
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Basic Information
Chromogranin A
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Hormonal / Endocrine ▸ Hormone peptide
Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
11 amino acids
C56H81N15O16
Standard
Sequence
AYGFRDPGPQL
Physicochemical Analysis
1220.33 Da
5.88
-0.20
-0.39
-0.0185
-0.76
0.40
0.00
18.88
44.55
0.1818
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
499.26
-4.22
16.0
16.0
34.0
87.0
4.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0087117 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Chromogranin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Chromogranin A (Rattus norvegicus): PMID 12716136 PMID12716136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12716136/
RECORD: Rec_0201416 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Chromogranin/secretogranin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secretory granule peptide Neuropeptide precursor
PMID12716136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12716136/
RECORD: Rec_0243627 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0306591 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Chromogranin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Metabolic regulation Physiological regulation Myotropic Receptor modulation Immunomodulatory
inhibits catecholamine release from chromaffin cells
Mammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Chromogranin A (Rattus norvegicus): PMID 12716136 PMID12716136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12716136/
RECORD: Rec_0402222 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]; Rattus norvegicus [Animal]
10090, 10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide