‹ ›
MYP_058644
← PREVIOUS NEXT → BACK
Basic Information
PRW4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
16 amino acids
C107H179N39O18
Standard
Sequence
RFRRLRWKTRWRLKKI
Physicochemical Analysis
2299.82 Da
12.00
8.76
8.55
0.5473
-1.64
0.27
-0.84
118.20
73.12
0.1875
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1001.09
-5.15
41.0
27.0
80.0
164.0
5.0
15.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0169092 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Salmonella Typhimurium 7731
8 μM
MIC
PaperDesign of imperfectly amphipathic alpha-helical antimicrobial peptides with enhanced cell selectivity.
RECORD: Rec_0177116 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis 12228
16 μM
MIC
PMID25735802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25735802/
RECORD: Rec_0184172 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
HaCaT cells
cytotoxicity assay
PMID25735802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25735802/
RECORD: Rec_0190421 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis 11060
18.4 μg/mL
MIC
PMID25818457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25818457/
RECORD: Rec_0196986 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli UB1005
9.2 μg/mL
MIC
PaperCharacterization of cell selectivity, physiological stability and endotoxin neutralization capabilities of α-helix-based peptide amphiphiles. Biomaterials. 2015 Jun;52:517-30. doi: 10.1016/j.biomaterials.2015.02.063. PMID: 25818457. PMID25818457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25818457/
FIRST PREV 1 2 3 4 5 6 ... 9 NEXT LAST
Showing 5 records · Page 4 of 9